Biomedical Engineering Courses (BME)


The following courses, numbered 5000-9999, are offered for graduate credit. Courses numbered 5000-6999 which are offered for undergraduate credit only may be found in the undergraduate bulletin, as well as all other undergraduate courses (numbered 0900-4999). Courses in the following list numbered 5000-6999 may be taken for undergraduate credit unless specifically restricted to graduate students as indicated by individual course limitations. For interpretation of numbering system, signs and abbreviations, see University Courses.

5005 Introduction to Cell Biology and Physiology for
Engineers. Cr. 2

Undergrad. prereq: senior standing. For any class designated as Web, contact online: (http://www.classschedule.wayne.edu). Basic understanding of fundamental human physiology for engineering students; emphasis on body function. (T)

5010 Engineering Physiology. (CHE 5100) (ECE 5100)
(I E 5100) (M E 5100) Cr. 4

Prereq: senior standing. Basic principles of human physiology presented from the engineering perspective. Bodily functions, their regulation and control discussed in quantitative terms and illustrated by simple mathematical models where feasible. (F,W)

5020 Computer and Mathematical Applications in Biomedical Engineering. Cr. 4

Prereq: proficiency in at least one programming language. Application of numerical methods in biomedical engineering. Data acquisition, reduction, and analysis using numerical methods and computer programming for such tasks. (F,W)

5030 Introduction to Molecular Biology for Engineers. Cr. 3

Prereq: BME 5010, BMS 5550, or college-level cell biology course. Introduction to cell biology and molecular biology for engineers interested in biomedical engineering. (F,W)

5040 Fundamentals of Engineering Analysis. Cr. 2

Open only to students without an engineering background. Prereq: consent of adviser. Intensive, self-directed course in engineering analysis from Calculus I through linear algebra and differential equations. Analytical foundation for graduate study in biomedical engineering for students with non-engineering backgrounds. (T)

5130 Vehicle Safety Engineering. Cr. 4

Role of vehicle in road safety, occupation and pedestrian injury mechanisms, measures of vehicle safety performance, driver behavior and vehicle interface. Use of new technology to improve vehicle safety. (F)

5210 Musculoskeletal Biomechanics. (M E 5160) Cr. 4

Prereq: BME 5010 or BMS 5550; M E 2400. Structure and properties of the major tissue components of the musculoskeletal sytem and evaluation of how tissues combine to provide support and motion to the body. (W)

5250 Spine and Hip Fractures in the Elderly. Cr. 2

Etiology and sequela of age-related fracture. Methodologies for detection and treatment of osteoporosis. Predictors of fracture risk.
(B)

5310 Device and Drug Approval and the FDA. Cr. 3

Prereq: BME 5010 or consent of instructor. Government regulations and industrial procedures that lead to device/drug approval. (B:W)

5370 Introduction to Biomaterials. (M E 5180) (MSE 5180)
Cr. 4

Prereq: B E 1300, BME 5010 or BMS 5550. Introduction to study of both biological materials (bone, muscle, etc.) and materials for medical applications. Topics include tissue properties and effects of pathology, biocompatability, and design considerations. (Y)

5380 Biocompatibility. (MSE 5385) Cr. 4

Prereq: BME 5010 or BMS 5550. Wound healing and the tissue response to foreign materials. The organization, activation, and mechanisms of the immune system. Bioactive materials and the molecular basis for surface recognition and masking. (B)

5390 Experimental Methods for Biomaterials. (MSE 5390)
Cr. 2

Hands-on and demonstration exposure to laboratory techniques for the assessment of biological tissues and artificial biomaterials. (Y)

5530 (ECE 5370) Mechatronic System Design I. Cr. 4

Prereq: ECE 4600 or equiv.; written consent of instructor. Students work in small groups to design and build `smart' devices or systems which will integrate sensors, digital logic and/or microprocessors, and user interfacing. The products will be requested by "clients" and the student will work in cross-disciplinary teams. (F)

5540 (ECE 5380) Mechatronic System Design II. Cr. 4

Prereq: ECE 4600 or equiv.; written consent of instructor. Continuation of BME 5530. (F)

5570 (Design of Human Rehabilitation Systems. (ECE 5170)
(I E 5170) (M E 5170) Cr. 4

Prereq: senior standing. Design, fabrication and testing of customized hardware to aid handicapped patients. (F)

5900 National Design Competition Projects. Cr. 1-4

Prereq: consent of instructor. Course allows BME students to participate in national projects competitions. (T)

5990 Directed Study. Cr. 1-4

Prereq: senior standing and written consent of program director. Independent projects on subjects in the field of biomedical engineering. (T)

5995 Special Topics in Biomedical Engineering I. Cr. 1-4

Topics as announced in Schedule of Classes. (I)

6470 (ECE 6570) Smart Sensor Technology I: Design.
(PHY 6570) Cr. 4

Prereq: B.S. degree in engineering or science. Introduction to various types of sensors and the design of basic analog VLSI circuit building blocks. (F)

6480 Biomedical Instrumentation. (ECE 6180) (I E 6180)
(M E 6180) Cr. 4

Prereq: ECE 3300, BME 5010 or BMS 5550, and BME 5020. Engineering principles of physiological measurements. Signal conditioning equipment, amplifiers, recorders and transducers. Recent advances. (F)

6500 (ECE 6100) (ST) Enabling Technology. (O T 6620) Cr. 3-4

Prereq: consent of instructor. Principles of application of enabling technology: across life stages, for differing ethnic and cultural backgrounds, for individuals with varying functional abilities. (Y)

6991 Internship in Industry. Cr. 1-4

Prereq: consent of graduate adviser. Industrial internship in biomedical engineering. (T)

7010 Functional Anatomy. Cr. 4

Open only to BME doctoral students. Prereq: BME 5010. Gross dissection-based course designed to introduce students to the anatomical structures associated with major physiological functions important to biomedical engineering. Material fee as indicated in the Schedule of Classes (F)

7030 Mechanisms and Models of Cellular Regulation for
Engineering. Cr. 3

Open only to graduate students. Prereq: BME 5030. Basic concepts of intracellular signaling pathways in response to environmental stimuli such as biomaterials and mechanical forces. (W)

7100 Mathematical Modeling in Impact Biomechanics.
(ECE 7100) (I E 7100) (M E 7100) Cr. 3-4

Prereq: M E 3400, and BME 5010 or BMS 5550; consent of instructor. Review of models created for impact simulations. Regional impact simulation models. Human and dummy models subject to various restraint systems. (W)

7120 Applied Finite Element Methods in Biomechanical
Analysis. Cr. 4

Prereq: M E 5040. Structural, stress, and strain analysis of the human body and/or artificial implants, using realistic biomechanical data for relevant tissues and material. Theoretical background and applied analysis. (Y)

7160 Impact Biomechanics. (ECE 7160) (I E 7160) (M E 7160) Cr. 4

Prereq: M E 2400, and BME 5010 or BMS 5550. Biomechanical response of the body regions and the whole body to impact. Mechanisms of injury in blunt impact. Effects of restraints on injury reduction. Development of test surrogates such as dummies. (B:F)

7170 Experimental Methods in Impact Biomechanics. Cr. 4

Prereq: BME 6480, BME 7160. Lecture and laboratory combined; principles of impact testing; hands-on experience in use of impact-test equipment, including sled, pendulum, other types of impactors, and drop-test techniques. Material fee as indicated in the Schedule of Classes (Y)

7180 Advanced Topics in Impact Biomechanics. Cr. 4

Prereq: BME 7160. Formal seminar. Critical review and evaluation of the literature. (F)

7210 Tissue Biomechanics. (M E 7195) Cr. 4

Prereq: BME 5010 or BMS 5550; BME 5020, BME 5210. Tissue-level mechanical properties. Analytical models of hard and soft tissue mechanics. Soft tissue viscoelasticity, quasilinear viscoelasticity and biphasic theory. Wolff's law and bone remodeling, bone fatigue and microfracture. Form and function relationships from microstructure to macrostructure. Application of theoretical models to experimental data sets. (B:F)

7300 Advanced Topics in Biomaterials and Tissue
Biomechanics. (M E 7180) (MSE 7180) Cr. 4

Prereq: BME 5210 or 5370. Seminar format: advanced topics presented to the class; lectures by the instructor and by the participants based on literature reviews. Topics determined by student interest.
(B:F)

7370 Biomaterial Interfaces. Cr. 4

Prereq: BME 5370. Effects of topography and texture on the performance of biomaterials. Self-organization of biomembranes and supramolecular systems. (B)

7380 Advanced Biocompatibility. Cr. 4

Prereq: BME 5380. Seminar format; advanced topics investigated and presented by students. (B:W)

7390 (CHE 7390) Tissue Engineering and Hybrid Systems.
Cr. 4

Prereq: BME 5370, and CHE 7100 or BME 5020. Seminar and project based approach to the design, development, analysis and application of organ and tissue replacement systems which incorporate processed materials and living cells. (B:W)

7470 (ECE 7570) Smart Sensor Technology II:
Characterization and Fabrication. (PHY 7580) Cr. 4

Prereq: ECE 6570. The fabrication process; characterization of sensors; design of associated analog VLSI circuit. (W)

7610 Pathophysiology of Pain. Cr. 3

Neurophysiology of pain from nerve receptors in peripheral tissue to synaptic transmission in the central nervous system. Neurophysiology and biology of pain in the spine, hip, knee and muscle. (B:W)

7670 Experimental Methods in Neurophysiology. Cr. 2

Anesthetized animal models used to demonstrate and study EMG recordings, principles of compound nerve potentials, sensory recording from joint and muscle, and effect of inflammation on sensory nerve response. (Y)

7710 Magnetic Resonance Imaging. Cr. 4

Prereq: MAT 2150, ECE 3570, ECE 3580, BME 5020. Science and engineering of magnetic resonance imaging; relaxation times, signal concepts, Fourier imaging, sampling, filtering, and sequence design.
(B)

7990 Directed Study. Cr. 1-4

Prereq: written consent of instructor. Independent projects on subjects of interest in the field of biomedical engineering. (T)

7995 Special Topics in Biomedical Engineering II. Cr. 1-4

Prereq: consent of program director. Topics as announced in Schedule of Classes. (I)

7996 Research. Cr. 1-4

Prereq: consent of chairperson and adviser. Combined experimental and analytical study of a problem in the field of biomedical engineering. (T)

8070 Seminar in Biomedical Engineering. Cr. 1 (Max. 2)

Offered for S and U grades only. Lectures on biomedical engineering and related fields by guest speakers, faculty, and students. M. S. students are required to take one semester; Ph.D. students are required to take two semesters. (F,W)

8080 Doctoral Seminar in Biomedical Engineering. Cr. 1

Prereq: doctoral candidate standing. Offered for S and U grades only. Seminar and research discussion based on research projects of BME doctoral students. (B)

8470 (ECE 8570) Smart Sensor Technology Seminar.
(PHY 8570) Cr. 1

Prereq: ECE 6570, 7570. Technological advances. Interaction of research experience in smart sensors and integrated devices. (W)

8999 Master's Thesis Research and Direction. Cr. 1-8

Prereq: consent of adviser. (T)

9990 Pre-Doctoral Candidacy Research. Cr. 1-8 (Max. 10)

Prereq: consent of department. For Ph.D. program applicants. Offered for S and U grades only. Research in preparation for doctoral dissertation. (T)

9991 Doctoral Candidate Status I: Dissertation Research and Direction. Cr. 7.5

Prereq: consent of dissertation adviser; Ph.D. candidate in department. Required in academic-year semester following advancement to Ph.D. candidacy. Offered for S and U grades only. (T)

9992 Doctoral Candidate Status II: Dissertation Research and Direction. Cr. 7.5

Prereq: consent of dissertation adviser; BME 9991. Required in academic-year semester following BME 9991. Offered for S and U grades only. (T)

9993 Doctoral Candidate Status III: Dissertation Research and Direction. Cr. 7.5

Prereq: consent of dissertation adviser; BME 9992. Required in academic-year semester following BME 9992. Offered for S and U grades only. (T)

9994 Doctoral Candidate Status IV: Dissertation Research and Direction. Cr. 7.5

Prereq: consent of dissertation adviser; BME 9993. Required in academic-year semester following BME 9993. Offered for S and U grades only. (T)

9995 Candidate Maintenance Status: Doctoral Dissertation Research and Direction. Cr. 0

Prereq: consent of dissertation adviser; completion of 30 credits in BME 9999, or 9991-9994. Offered for S and U grades only. (T)

9999 Doctoral Dissertation Research and Direction.
Cr. 1-16 (Max. 16)

Prereq: consent of chairperson of program graduate committee. No more than 10 credits to be elected before doctoral candidacy. Offered for S and U grades only. (T)