The following courses, numbered 5000-9999, are offered for graduate credit. Courses numbered 5000-6999 which are offered for undergraduate credit only may be found in the undergraduate bulletin, as well as all other undergraduate courses (numbered 0900-4999). Courses in the following list numbered 5000-6999 may be taken for undergraduate credit unless specifically restricted to graduate students as indicated by individual course limitations. For interpretation of numbering system, signs and abbreviations, see University Courses.
Most laboratory courses have a non-refundable materials fee and are so indicated in the Schedule of Classes.
Prereq: BIO 3070 or 4130; MAT 1800. Quantitative methods in biology. Statistical approach to data analysis and the design of experiments. Laboratory section permits actual analysis of selected statistical problems. Material Fee as indicated in the Schedule of Classes (B)
Prereq: BIO 1500 or consent of instructor. Formalized treatment of the current state of knowledge in a significant area of biology. Topics to be announced in Schedule of Classes. (Y)
Relationship between behavior and neuroscience using a variety of animal models, each examined from the level of natural behavior progressively to the cellular level. Topics include: sensory systems, motor behavior, and learning. (W)
Prereq: 12 credits in biology, consent of instructor. Field studies of one to fifteen weeks, emphasizing biological principles and techniques demonstrated in the field. Material Fee as indicated in the Schedule of Classes (S)
Prereq: BIO 2200, 3100, 3070 or equiv. Review of origins of molecular biotechnology and its characteristic technologies; survey of applications of biotechnology to problems in industries. (F)
Prereq: BIO 1500 or 1520, and 2200. Principles of plant infection, structure and life cycle of plant pathogens, defense mechanisms, spread and control of plant disease. (S)
Prereq: BIO 1500 or 1520. Principles and methods of taxonomy and identification of native vascular plants. Material Fee as indicated in the Schedule of Classes (I)
Prereq. or coreq: BIO 5620. Slides, models, and 4-D computer programs used to enable the student to know and recognize the cascade of structural changes that take place during the embryological developmental pathways. Material Fee as indicated in the Schedule of Classes (W)
Prereq: BIO 3070. An analytical and comparative study of genetic and cellular mechanisms and their interaction with environmental factors to effect the developmental mechanisms which produce the adult organism. Origin and unfolding of structural patterns characteristic of different species; their evolutionary origins. (F)
Prereq: BIO 2870 or 4120. Characteristics and identification of normal mammalian tissues. Micro-anatomy of the mammal. Functional interpretation of microstructure and fine structure. Material Fee as indicated in the Schedule of Classes (F)
Prereq: BIO 4120; or consent of instructor. Introduction to integrated analysis of cancer and cell biology, pathology, etiology and therapy.
(F)
Prereq: PSL 3220 or BIO 4120 or equiv., or coreq: PSL 7010. Basic description of the human endocrine system, the endocrine control of several physiologic processes (growth, development, metabolism and reproduction), and a description of common endocrine disorders. (F)
Prereq: 16 credits in biology. Function, biological significance, causation, and evolution of species-typical behaviors which are part of the animal's behavioral repertoire under natural conditions. (I)
Prereq: 16 credits in biology. Life histories, survival and evolutionary strategies, laboratory and field identification, including study techniques of vertebrates; Michigan wildlife. Field trips. Material Fee as indicated in the Schedule of Classes (I)
Prereq: BIO 1500. Natural history, ecology and evolution of birds with emphasis on identification and field studies of Michigan birds. Material Fee as indicated in the Schedule of Classes (I)
Prereq: 16 credits in biology. Systematics, geographical distribution, ecology, adaptive radiation, patterns of growth and reproduction, physiology. Field trips. Material Fee as indicated in the Schedule of Classes (S)
Prereq: BIO 1500 or 1520. The systematics, classification, and functional morphology of insects; methods of collection and study of insect specimens. Material Fee as indicated in the Schedule of Classes (I)
Prereq: BIO 3070 or consent of instructor. Aging and senescence viewed as fundamental biological processes common to most organisms. Empirically-based discussion of investigative methods and accepted facts regarding aging, coupled with critical discussion of behavioral and biological interventions believed to retard or reverse the aging process; critical analysis of theoretical interpretations of this data. (W)
Prereq: BIO 4110 or 4120. Analysis of cell structure at the molecular and cellular levels and the physiological consequences of these structures: isolation, physico-chemical properties, and biological attributes of cells, organelles, and biopolymers including nucleic acids, proteins, and lipids. (F)
Prereq: BIO 6000. Analysis of cell regulation at the molecular level. Cell development and differentiation. Genetic mechanisms including: DNA synthesis and repair, mechanism of gene expression and control. (W)
Prereq: one year of chemistry and biology. Theory and application of instruments and procedures used in biological materials analysis. Topics include: error analysis, basic electronics, solutions and buffers spectroscopy, separation techniques, elemental analyses, laboratory application of computers. Material Fee as indicated in the Schedule of Classes (F)
Prereq: BIO 3070. Physical and chemical properties of the genetic material; the fundamental mechanisms concerned with its replication, function, mutation, recombination and regulation; molecular basis of evolution. A critical presentation of interdisciplinary subjects of biology, biochemistry and biophysics in relation to recent advances in genetic engineering. (Y)
Introduction to biology of eye structure/function, and to causes and clinical treatments of eye-related disorders and diseases. Material Fee as indicated in the Schedule of Classes (Y)
Prereq: BIO 3070 and 4200 or 4130. Patterns and processes of evolutionary change on the DNA sequence level. Emphasis on models of nucleotide substitutions, and genic evolution. Methods of phylogenetic inference. (I)
Prereq: BIO 3070. Principles of genetics as applied to humans. Topics include pedigree analysis, simple and complex inheritance patterns, cytogenetics, development and sex determination, role of mutations in disease, genes and cancer, genetic testing and forensics, genomics, linkage, genetics of behavior, and evolution. (B)
Prereq: BIO 3070 or equiv. Principles and current progress in genetics at the molecular and cellular levels. Emphasis on those features of microorganisms and cultured animal and human cells appropriate for the study of the fundamental mechanisms concerning recombination, replication, metabolic functioning. (Y)
Prereq: BIO 4200 or 4130. Theoretical bases for microevolutionary change in natural populations of organisms; basic to study of evolutionary genetics and evolutionary ecology. (B)
Prereq: BIO 6010 or written consent of instructor. Laboratory exercises illustrate methods and concepts of molecular biology and recombinant DNA analysis. Material Fee as indicated in the Schedule of Classes (Y)
Prereq: one year of biology, chemistry and physics. Analysis of the biologically important aspects of thermodynamics, chemical bonding, macromolecular structure, biomembranes and transport processes.
(W)
Prereq: one year of biology and chemistry; BIO 2200 or 4120; BIO 6000 or 6160 recommended. Comprehensive analysis of cellular and model membranes integrating molecular structure and physiological properties. Structural, dynamic, and physiological properties examined, including molecular and macromolecular assemblies, physical and chemical analysis of molecular motion, functional aspects including trans-membrane signalling. (Y)
Prereq: consent of instructor or department. Formalized treatment of current state of knowledge in a significant area of biology. Topics to be announced in Schedule of Classes. (I)
Open only to middle- or high school teachers. Prereq: teaching certificate; mathematics through algebra. Ecological principles such as energy and nutrient flow demographics and populations; population genetics; genetics and phylogeny. (W)
Open only to middle- or high school teachers. Prereq: teaching certificate. Prokaryotic and eukaryotic cell structure and function; basic biology and recent advances. (W)
Open only to middle- or high school teachers. Prereq: teaching certificate; mathematics through algebra. Introductory prokaryotic and eukaryotic gene structures and functions of mechanisms of inheritance. (S)
Prereq: BIO 2600; teaching certificate. Open only to middle or high school teachers. For any class designated as Web, contact online: (http://www.classschedule.wayne.edu). Theories and technologies in the use of genomics; proteomics and bioinformatics techniques currently used for research and commercial applications. Web-based course. (Y)
Prereq: consent of instructor. Offered only for graduate credit; for teachers only. Discussion of basic biological principles in light of recent advances. (Y)
Prereq: consent of instructor. Offered only for graduate credit; for teachers only. Laboratory component of BIO 6250; basic laboratory techniques in light of recent advances in the biological sciences. Material Fee as indicated in the Schedule of Classes (Y)
Prereq: BIO 5330 or written consent of instructor. Application of molecular biology and recombinant DNA technology of contemporary eukaryotic systems. Topics include: specialized application of PCR for cloning, generation of antibodies, the expression of recombinant proteins in cultured cells and transgenic animal models. (W)
Prereq: BIO 4130. Systematics, physiology and ecology of algae and higher aquatic plants. Material Fee as indicated in the Schedule of Classes (I)
Prereq: BIO 4130 or 4200 or equiv. Continuation of BIO 4130; emphasis on evolutionary biology. Topics include: history of evolutionary thought, origins of life, evolution of the cell, evolution of genes, evolution and behavior, evolution of life history traits, phylogenetics, historical biogeography, tempo and mode of evolution, species concepts and speciation, nature of adaptation and adaptive radiations. (B)
Prereq: BIO 4130. Discussion and analysis of recent topics in ecological theory. (I)
Prereq: written consent of instructor obtained in semester prior to registration; introductory biology and organic chemistry recommended. Intensified two-week program at a marine biological station. In-depth study of comparative physiology and biochemistry of marine animals. Daily field collecting, laboratory sessions and evening lectures. Individualized research projects; presentation at concluding symposium. Material Fee as indicated in the Schedule of Classes (S)
Prereq: BIO 4120 and 3100. Electrical and chemical signal transmission and signal processing in the nervous system. Integration of these functions into complex sensory and control mechanisms. Molecular mechanisms of electrical excitability and ion channels, neurotransmitters and receptors, second messengers, and feedback circuits. Neurobiology of motor control, sensory and regulatory systems. (F)
Prereq: CHM 2260 and BIO 1510 or equiv. Not applicable for biological sciences major credit. Mechanisms of action and metabolism of commonly-used drugs and toxic substances from the cellular level to whole biological systems. (Y)
Prereq: admission to molecular biotechnology program or consent of instructor. Methods of written and oral communication in the biotechnology field. (W)
Prereq: written consent of instructor. Formalized and in-depth treatment of the current state of knowledge in a significant area of cell and molecular biology. Topics to be announced in Schedule of Classes .
(I)
Prereq: CHM 2260 and BIO 1510 or equiv. recommended. Basic concepts and principles of toxicology, including toxicity of major classes of chemicals (pesticides, solvents, metals) and organ systems (renal, immune, digestive, neuro and respiratory) affected. (F)
Prereq: BIO 3070. Physical and chemical properties of the genetic material; the fundamental mechanisms concerned with its replication, function, mutation, recombination and regulation; molecular basis of evolution. A critical presentation of interdisciplinary subjects of biology, biochemistry and biophysics in relation to recent advances in genetic engineering. (Y)
Integrated introduction to basic biological structure/function of the eye; causes and clinical treatments of eye-related disorders and diseases. (F)
Prereq: BIO 3070 or equiv. Principles and current progress in genetics at the molecular and cellular levels. Emphasis on those features of microorganisms and cultured animal and human cells appropriate for the study of the fundamental mechanisms concerning recombination, replication, metabolic functioning. Includes independent studies. (Y)
Prereq: BIO 5620. An examination of the current and classical research literature dealing with the role of gene action in development. (B)
Prereq: consent of instructor. Formalized and in-depth treatment of current state of knowledge in a significant area of microbiology and molecular genetics. (B)
Prereq: BIO 3070. Molecular basis of organogenesis in vascular plants. Current advances in plant development. Potential bases of morphological diversity and evolutionary change. (B)
Prereq: BIO 1500 or 1520, and 2200. Principles of plant infection, structure and life cycle of plant pathogens, defense mechanisms, spread and control of plant disease. (B)
Prereq: BIO 3070, 3100 or equiv. Detailed analysis of structure, expression and replication off genes of prokaryotic cells and associated extrachromosomal elements. Critical discussion of studies establishing central concepts in prokaryotic gene regulation, DNA structure and dynamics and nucleic acid enzymology. In-depth examination of molecular-genetic methodologies used in experimental investigations of prokaryotic systems. (Y)
Prereq: BIO 6330 or 7780. Knowledge of current molecular technology is absolute prerequisite for this course; prerequisite course must have been satisfied. Analysis of structure, replication, expression and regulation of eukaryotic genome. Experimental approaches to study eukaryotic gene expression, critical comprehension of current research, design of experiments in gene expression. (Y)
Prereq: BIO 6690 or consent of instructor. Advanced topics; emphasis on neurodevelopment using model systems, and possible molecular mechanism; models of higher order functions: learning, memory behavior, cognition; human disease and recent genetic characterization. (W)
Prereq: consent of instructor obtained in semester prior to registration; introductory biology and organic chemistry recommended. Intensified two-week program at a marine biological station; in-depth study of comparative physiology and biochemistry of marine animals. Daily field collecting, laboratory sessions, and evening lectures. Individualized research projects; presentation at concluding symposium
. (S)
Prereq: BIO 3070 or consent of instructor. Aging and senescence viewed as fundamental biological processes common to most organisms. Discussion of investigative methods and accepted facts regarding aging; critical analysis of theoretical interpretation of the data. (W)
Prereq: BIO 6120, 6330, or written consent of program director. Continuation of BIO 6120 laboratory experience; screening procedures and DNA sequencing methods. Material Fee as indicated in the Schedule of Classes (Y)
Prereq: written consent of adviser or instructor. Original investigation. (T)
Prereq: written consent of instructor. Various frontier aspects of biology. Work may include lectures, laboratories or discussion. Topics to be announced in Schedule of Classes. (Y)
Prereq: graduate standing in biology. One semester required for research master's students; two semesters required for doctoral students. Presentations by graduate staff, advanced students, visiting lecturers. (Y)
Prereq: admission to biotechnology program or consent of instructor. Students spend two semesters doing research under the guidance of faculty associated with the Molecular Biotechnology Program and in other laboratories. (W,S)
Prereq: written consent of instructor. (T)
Prereq: consent of department. For Ph.D. program applicants. Offered for S and U grades only. Research in preparation for doctoral dissertation. (T)
Prereq: consent of dissertation adviser; Ph.D. candidate in department. Required in academic-year semester following advancement to Ph.D. candidacy. Offered for S and U grades only. (T)
Prereq: consent of dissertation adviser; BIO 9991. Required in academic-year semester following BIO 9991. Offered for S and U grades only. (T)
Prereq: consent of dissertation adviser; BIO 9992. Required in academic-year semester following BIO 9992. Offered for S and U grades only. (T)
Prereq: consent of dissertation adviser; BIO 9993. Required in academic-year semester following BIO 9993. Offered for S and U grades only. (T)
Prereq: consent of dissertation adviser; completion of 30 credits in BIO 9999, or 9991-9994. Offered for S and U grades only. (T)
Prereq: consent of doctoral adviser. Open only to doctoral students and Plan A master's students. Research training in faculty laboratories on a rotating basis, up to two labs per semester. (T)
Prereq: written consent of doctoral adviser. Offered for S and U grades only. (T)